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  • 15.05.2018
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Strep pneumonia in older adults

Little is known about pneumococcal carrier states in older adults. The main aim of this study was to evaluate pneumococcal colonization patterns among older adults in two centres in Milan, Italy, before the widespread use of the valent pneumococcal vaccine PCV13 in this age group, to investigate demographic and clinical features that are associated with pneumococcal colonization and to estimate the potential coverage offered by PCV Univariate and multivariate analyses revealed that pneumococcal colonization was significantly less common among individuals with underlying co-morbidities than among those without odds ratio [OR] 0. Moreover, among these patients, those with cardiac disease had a significantly lower risk of colonization OR 0. Only one vaccinated subject who received valent polysaccharide pneumococcal vaccine PPV23 was colonized.
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Pneumococcal colonization in older adults

Strep pneumonia in older adults
Strep pneumonia in older adults
Strep pneumonia in older adults
Strep pneumonia in older adults
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Pneumococcal vaccination in older persons: where are we today?

Community-acquired pneumonia CAP is an increasing problem among the elderly. Multiple factors related to ageing, such as comorbidities, nutritional status and swallowing dysfunction have been implicated in the increased incidence of CAP in the older population. Moreover, mortality in patients with CAP rises dramatically with increasing age. Streptococcus pneumoniae is still the most common pathogen among the elderly, although CAP may also be caused by drug-resistant microorganisms and aspiration pneumonia.
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Pneumococcal vaccination in older persons: where are we today?

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Disease due to Streptococcus pneumoniae , the pneumococcus, remains a major source of illness in older persons. Globally, it remains the most important pathogen in respiratory infection deaths. Conjugated pneumococcal vaccines are used extensively in national pediatric programs, whereas a polysaccharide vaccine is used in all age groups, but mainly in the elderly and for high-risk groups.
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